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Functions of IGF-1: Cell Growth and Development: IGF-1 stimulates systemic body growth by affecting almost every cell in the body, particularly skeletal muscle, cartilage, bone, liver, kidney, nerve, skin, hematopoietic, and lung cells

We visualized single-cell data via principal component analysis (PCA) considering only the expression of proteins associated with cellular metabolism (GLUT1, HK, GAPDH, LDHA, G6PD, CD98, CS, ATP5A, CD36, CPT1A, ACADM, ACLY, FASN, SCD1, LAL, mTOR, pAKT, pS6, AMPK), and determined that CAR T cells from STR and LTR have distinct metabolic states (Fig